Anyone who thinks a turbo engine will be as reliable as a N/A engine, has clearly never owned a turbo engine long term. The seals will fail on the turbo. They all fail. In this case, there are two to replace. Jen 2s can pretty much count on a $1500 bill to replace the turbos at some point. Double that if you are paying someone else to do the work.
Let's not even go into what to does to the life of the cooling system, exhaust system EGR system, PCV system, and the intake system. All of the extra heat and pressure is not good for those systems.
Just a basic example... If you were an intake manifold gasket, would you rather live your life in an engine where the manifold is either just sitting on the top of the engine or is being sucked down tight to the engine with vacuum, or would you rather be on an engine where the manifold quickly and frequently goes back and forth from being sucked down onto the heads to being pushed off of the heads by boost pressure?
I'm guessing this intake is plastic too? Uggh. Vacuum, pressure, vacuum, pressure- repeat 100,000 times at super hot and freezing cold temps and see if that plastic holds up. Probably does fine in the accelerated test Ford uses, probably not as robust in the real world.