good question.
after you get it dialed in, I'd say the daily drive is about 15% less "plush" than when it was stock. If you are going to do Toyo's or similar, my suggestion is put those on first and drive stock suspension so you can realize that you lose about 30% of your "plush" ride moving off the BFG's.
What I have noticed:
micro adjustments as the steering is more repsonsive. there is less slop in the steering so you will adjust for things (side drafts, ruts in the pavement) that you never used to notice.
No sway bar - I honestly only notice it on faster turns where the truck will want to crab sideways a bit.
what I have not noticed:
speed bumps, small animals, Priuses. truck just floats over them.
My truck spends about 75 to 80% of it's life on road, and since I've had this done, it just makes me look forward to the 20-25% time more and more. If your truck isn't going to get some good offroading, I'd probably look at spending the money on other mods, but if you want to join RASA (tm) - Raptor Air and Space Administration - this is the launch pad for you.