Update
Update: I had some type of a rattling and/or crackling sound coming from the speakers. I removed the door panels today to investigate. 2 things happened.
1. The weather strip foam I used must have compressed because both speakers were a little loose.
2. I also discovered that the passenger side speaker wire harness was wet.
I removed the foam and applied 3 layers of Dynamat around the speaker opening to give a better surface for the speaker to sit against and also close the small gaps around the speaker opening. The goal here isn't sound deadening but just to promote a solid mounting surface and seal around the speaker opening.
I also used a strip of Dynamat to wrap the speaker wire plug to create a water tight envelope around the plug and wires. I then routed the excess wire around another harness in the door to keep it away from the window when it's down because I think that is where the water came from.
I put it all back together and I think I have remedied the rattling noise. I believe the crackling noise could have been from the connections being wet? Or it could be poor audio quality from my iPod...not sure.