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You aren't gaining 200hp with a downpipe and a tune.
F150 FreakOBoost Twin EFR Turbo Kit – Full Race
^^^ that's what it took to break 500hp in a gen 1 f150 eco.
Gen 2 HO eco has larger turbo's, etc etc, probably looking at 120-150 with fairly easy upgrades (charge piping, intercooler, tune, downpipe). More if you throw in tubular manifolds, ported hot side, etc.
The numbers are there, but you'll have to pay like everyone else.
Danzio sells an 830hp/600tq eco for 40k but it has lots of custom goodies.
https://www.danzioperformance.com/?page_id=13
Just for reference. You CAN get 200hp from a tune and a new downpipe on some engine platforms. You should look into some of the APR Tunes for some of the Audi's
https://www.goapr.com/products/ecu_upgrade_40tfsi_rs6rs7.html
This thread isn't about Audi's. I said you won't get 200hp with a downpipe and a tune with this ecoboost.
You never said "with this ecoboost" but ok. 200hp extra is probably possible. New engine, new internals and a good bit of r&d on making sure the engine is overbuilt to survive the 450hp. Don't say it's not possible when you don't know.
Somebody with a truck needs to get a good picture of the housing of a turbo and the stampings on it and then we can formulate a very, very good estimate of what this engine will be capable of on those turbos.