Shock pressure makes a big difference as well. When I first installed my DSC's I was at 180PSI. They felt great on road off-road very soft even when I increase stiffness.
Went to 200PSI and it was night and day... still a great ride however off-road they were not soft at all and felt great on 2' whoops. Going to 220PSI this weekend and I will see how it feels with our Destination Mint 400 next month
As for settings, like @RDFTS I keep them fully open on the street. Off-Road I go 7 clicks in on high speed (blue) and leave slow speed open.
How do you increase or decrease the PSI ?