25% coverage on the dynamat is all you need. Place it on the portions of the sheet metal that are furthest from supports. If you knock on the panel with your knuckle every time you add a chunk you will quickly be able to tell when you have hit the threshold, make sure you are pressing it on thoroughly, if it isn't stuck down well it wont work. Dynamat doesn't absorb or block noise in the frequency spectrum your interested in but it will keep the panels from resonating and amplifying it. Start with whatever dampener (dynamat, KnoNoise, whatever) and see how you like that, if your still not satisfied mass loaded vinyl over an isolator in the doors, rear of the cab and floors really helps, then some hydrophobic melamine for absorbtion, preferably in the roof and kick panels. I've done this treatment on a few vehicles, even the 78 f150 turbocharged 460 with 5" exhaust is nice to be in... so long as you have the windows up.